Background: In order to anticipate the diagnosis of Multiple Sclerosis (MS), the diagnostic criteria had been reviewed several times in the last years. Objective: We wanted to understand whether earlier diagnoses of MS have impacted on therapeutic management of the disease. Methods: We designed a 22-item survey posted on SMsocialnetwork, a webplatform with a medical supervision, dedicated to Italian MS patients. We collected socio-demographic data, disease and treatment-related information of 1000 patients. Results: The median age at diagnosis significantly decreased over years. In the last decades the time delay between disease onset and diagnosis reduced, the disease phenotypes at diagnosis shifted from progressive form to relapsing ones and clinically isolated syndrome, the number of early treated patients increased over time. Conclusion: We showed, verifying a large sample of patients in a reallife setting, that the improvement of the diagnostic process allowed the anticipation of MS diagnosis over years and had a huge impact in terms of treatment approach.

Impact of early diagnosis on clinical characteristics of an Italian sample of people with multiple sclerosis recruited online / Lavorgna, Luigi; Borriello, Giovanna; Esposito, Sabrina; Abbadessa, Gianmarco; Capuano, Rocco; De Giglio, Laura; Logoteta, Alessandra; Pozzilli, Carlo; Tedeschi, Gioacchino; Bonavita, Simona. - In: MULTIPLE SCLEROSIS AND RELATED DISORDERS. - ISSN 2211-0348. - 27:(2018), pp. 239-246. [10.1016/j.msard.2018.10.113]

Impact of early diagnosis on clinical characteristics of an Italian sample of people with multiple sclerosis recruited online

Borriello, Giovanna;De Giglio, Laura;Logoteta, Alessandra;Pozzilli, Carlo;Bonavita, Simona
2018

Abstract

Background: In order to anticipate the diagnosis of Multiple Sclerosis (MS), the diagnostic criteria had been reviewed several times in the last years. Objective: We wanted to understand whether earlier diagnoses of MS have impacted on therapeutic management of the disease. Methods: We designed a 22-item survey posted on SMsocialnetwork, a webplatform with a medical supervision, dedicated to Italian MS patients. We collected socio-demographic data, disease and treatment-related information of 1000 patients. Results: The median age at diagnosis significantly decreased over years. In the last decades the time delay between disease onset and diagnosis reduced, the disease phenotypes at diagnosis shifted from progressive form to relapsing ones and clinically isolated syndrome, the number of early treated patients increased over time. Conclusion: We showed, verifying a large sample of patients in a reallife setting, that the improvement of the diagnostic process allowed the anticipation of MS diagnosis over years and had a huge impact in terms of treatment approach.
2018
Disease modifying treatment; Early diagnosis; Multiple sclerosis; Web-based survey; Neurology; Neurology (clinical)
01 Pubblicazione su rivista::01a Articolo in rivista
Impact of early diagnosis on clinical characteristics of an Italian sample of people with multiple sclerosis recruited online / Lavorgna, Luigi; Borriello, Giovanna; Esposito, Sabrina; Abbadessa, Gianmarco; Capuano, Rocco; De Giglio, Laura; Logoteta, Alessandra; Pozzilli, Carlo; Tedeschi, Gioacchino; Bonavita, Simona. - In: MULTIPLE SCLEROSIS AND RELATED DISORDERS. - ISSN 2211-0348. - 27:(2018), pp. 239-246. [10.1016/j.msard.2018.10.113]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1197904
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 12
  • ???jsp.display-item.citation.isi??? 11
social impact